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Other names: Zimulti
Acomplia (Rimonabant)
THE COMPOSITION OF THE SKIN

Our skin, which is the largest organ in the body, is our presentation to the world. It also keeps us at a comfortable temperature and is our first line of defense against environmental injury.
That we value the attractiveness of our skin is proven by the billions of dollars we spend on skin cosmetics. If our skin is diseased or has abnormalities (even minor ones), this can cause considerable anxiety and depression as self-esteem and self-confidence are closely linked to the way we see ourselves.
The skin is composed of two major layers. The outer layer, the epidermis, is mainly responsible for protection. The inner layer, the dermis, forms the structural foundation and gives the skin its mechanical strength and elasticity. These two layers lie on top of a fat layer which provides a soft, cushioning contour to the body.

The epidermis
An injured or diseased epidermis can cause greater than normal water evaporation, producing cracking and dryness. This enables foreign chemicals and/or infection to penetrate the skin, leading to deeper damage. The epidermis is a self-sufficient, self-regulating structure. New cells are made every twenty-eight days and old cells are gradually removed from the surface. If the epidermis is injured or diseased, however, cells are made more quickly.
Within the epidermis are pigment cells. These produce melanin, a dark brown to black pigment that is spread throughout the dermis. Melanin absorbs ultraviolet light, thus protecting the skin from the sun’s damaging effects. People with more pigment, such as Aborigines and Asians, are therefore better protected from sunlight.
Immune cells called Langerhan’s cells are also found in the epidermis. These cells migrate through the skin, behaving as a warning device. They alert the immune system to the presence of foreign bodies which should be removed. If the immune cells are overexposed to ultraviolet light, they become paralyzed and so are less able to protect the skin.

The dermis
The strength and elasticity of the dermis allow the skin to stretch with movement and growth. A good example of this occurs during pregnancy, when the skin expands to accommodate the growing foetus, then contracts after delivery with little damage to the skin. This is a remarkable feat of nature which we take for granted. If growth is very rapid, however, the fibres that form the dermis can break, producing what we aptly call ’stretch marks’. The dermis also loses its strength and elasticity if exposed to ultraviolet light over a long time. This leads to sagging, wrinkling and fragile skin, which is so obvious in prematurely aged skin.

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