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Aerolate, Theo-24 (Theophylline)

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Other names: Quibron-T, Slo-bid Cr, Slo-phyllin Cr, Theolair Cr, T-phyl Cr, Uni-dur Cr, Uniphyl Cr
TREATMENT OF ALLERGY

In common parlance the term allergy is used to describe an unusual sensitivity but, strictly speaking, it should be confined to an altered reactivity on a second or subsequent exposure to a stimulus.
Some patients get headaches in response to an allergic reaction, possibly due to release of histamine. With the implication that food allergy plays a part in producing migraine, attempts have been made to desensitize patients to offending substances. This involves testing for allergy by using small amounts of suspected materials and noting those to which there is a response. This substance is then prepared in minute concentrations and increasing amounts are injected under the skin at frequent intervals in order to increase gradually the body’s tolerance to it. This approach works well in hay fever and some cases of asthma, where there are definite identifiable allergic responses, but the situation in migraine is not as clear-cut. Although some migraine sufferers may have demonstrable food allergy, desensitizing them to the offending food does not always confer benefit. A trial of this form of treatment in a large number of people is needed, comparing results with those in another group of people who had been ‘desensitized’ with an ineffective substance. This sort of trial has not been undertaken and, in the present unsatisfactory situation, those with demonstrable allergy to a particular substance should take advice from specialists in the field, because of the possibility that they will experience some benefit from desensitization.

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